The substrate specificity and conformational flexibility of ketosteroid hydroxylases

3-Ketosteroid-9α-hydroxylase (KshAB) is a Rieske oxygenase involved in bacterial steroid degradation. Bacteria such as Rhodococcus rhodochrous DSM43269 harbor up to five KshA homologues (numbered 1 to 5) that appear to be involved in degrading different steroids. Previous work indicated that KshA5 (...

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Bibliographic Details
Main Author: Penfield, Jonathan
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/45138