Towards the synthesis of Janus-AT phosphoramidites

A Janus heterocycle is one kind of heterocycle that possesses hydrogen bonding donors or acceptors at both sides compared to regular nuclear bases. This provides an interesting synthetic target as well as a tool for testing an intriguing biological hypothesis related to DNA recognition, namely can b...

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Bibliographic Details
Main Author: Liu, Wenbo
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44982