Exploring the genetic interactome of a Saccharomyces cerevisiae separase mutant

The budding yeast Saccharomyces cerevisiae is used as a model organism for understanding cellular dynamics such as cell cycle regulation. Separase endopeptidases are essential to these events, being responsible for cleavage of cohesin – the molecular glue holding sister chromatids together. To exami...

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Bibliographic Details
Main Author: Ho, Krystina
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44279