Towards specific inactivators of Trypanosoma cruzi trans-sialidase

The Trypanosoma cruzi (T. cruzi) trans-sialidase is thought to be an essential enzyme for infection by T. cruzi since sialic acid is needed for its nutrition and pathogenesis yet T. cruzi cannot biosynthesize sialic acid. The overall goal of this project is to identify a tight binding and specific i...

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Bibliographic Details
Main Author: Yao, Yuan
Language:English
Published: University of British Columbia 2013
Online Access:http://hdl.handle.net/2429/44074