Microfluidic technologies for rapid, high-throughput screening and selection of monoclonal antibodies from single cells

This thesis describes the development of novel microfluidic technologies for rapid, high-­‐throughput screening and selection of monoclonal antibodies (mAbs) from single cells. Microfluidic devices were used to compartmentalize single antibody-­‐ secreting cells (ASCs) in small-­‐volume chambers (i....

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Bibliographic Details
Main Author: Singhal, Anupam
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/43575