Effects of sleep-deprivation on long-term depression of excitatory synaptic transmission in the ca1 region of the hippocampus

In the central nervous system (CNS), synapses are considered to be the loci for memories. Activity dependent strengthening or weakening of synaptic strength via long-term potentiation (LTP) or depression (LTD), respectively, is widely postulated to underlie memory formation. Sleep, which is universa...

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Bibliographic Details
Main Author: Tadavarty, Ramakrishna
Language:English
Published: University of British Columbia 2012
Online Access:http://hdl.handle.net/2429/40972