The role of endogenous retinoic acid in jaw development

The aim of this thesis is to study the effects of reducing retinoic acid (RA) levels in the embryonic face on jaw morphogenesis. One member of the Cytochrome P26 class of enzymes, CYP26A1, which degrades retinol products, was locally overexpressed in chicken embryos. I hypothesized that lowering RA...

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Bibliographic Details
Main Author: Fan, Churmy Yong
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/37477