Comprehensive identification of nitroxyl-reactive cysteines in human platelet proteins by quantitative mass spectrometry
HNO, a small compound which can be produced upon hydrolysis of Angeli’s Salt, is known to be able to inhibit platelet aggregation. An important step to elucidate the mechanism of the antiaggregatory effect of HNO and define the drug’s targets is the identification of HNO-reactive proteins in platele...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/37089 |