Developing novel therapeutics for excitotoxic neuronal death following stroke

Ischemic stroke is a major cause of death and disability in developed countries, and a major economic burden in the world. The mechanisms mediating stroke damage are likely multifactorial, with N- methyl-D-aspartate receptor (NMDAR) mediated excitotoxicity being an important factor. But NMDAR blocke...

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Bibliographic Details
Main Author: Lai, Ted
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/36645