Stereoselective total synthesis of sesquiterpenoids; (-)-copacamphene and (-)-cyclocopacamphene
An efficient, 6-step synthesis of the (-)-diketone (122) from (+)-carvomenthone (123) is described. Conversion of 123 Into the corresponding n-butylthiomethylene derivative (131), followed by alkylation of the latter with ethyl 2-iodopropionate and successive removal of the n-butythiomethylene bl...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/32873 |