Thietane 1, 1-dioxide derivatives as potential analgetics of the methadone type
Thietane 1,1-dioxide derivatives were synthesized as potential narcotic analgetics of the methadone type. Thietane 1,1-dioxides are con-formationally more restricted than methadone and thus may be useful in elucidating the pharmacophoric conformation of methadone and related analgetics. The react...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/32516 |