Using magnetic resonance imaging and immunohistochemistry to monitor the response of HCT-116 xenograft tumours to tirapazamine

Tirapazamine is a prodrug which is activated under hypoxic conditions and has shown promise in treating hypoxic tumours. Using MRI and histochemistry, the response of HCT116 xenograft tumours to tirapazamine was investigated and quantified. Dynamic contrast-enhanced and diffusion weighted MRI sc...

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Bibliographic Details
Main Author: Bains, Lauren Jean
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/31832