Genetic control of the teratogenic response to acetazolamide in mice

Acetazolamide is a potent carbonic anhydrase inhibitor and a known teratogen. In mice, it Induces a specific postaxial ectrodactyly of the right forelimb; occasionally the left forelimb is also affected. No other malformations are produced by this drug except fetal death with high doses. The SWV st...

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Bibliographic Details
Main Author: Biddle, Frederick Gordon
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/31821