Genetic control of the teratogenic response to acetazolamide in mice
Acetazolamide is a potent carbonic anhydrase inhibitor and a known teratogen. In mice, it Induces a specific postaxial ectrodactyly of the right forelimb; occasionally the left forelimb is also affected. No other malformations are produced by this drug except fetal death with high doses. The SWV st...
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Language: | English |
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University of British Columbia
2011
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Online Access: | http://hdl.handle.net/2429/31821 |