An intratumoral controlled release formulation of clusterin antisense oligonucleotide and paclitaxel or docetaxel for treatment of prostate tumors

The localized controlled delivery of both phosphorothioated clusterin antisense oligonucleotide (clusterin ASO) and paclitaxel or docetaxel to prostate tumors to maintain therapeutic concentrations of the agents at the target disease site was investigated in this work. The primary objectives were...

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Bibliographic Details
Main Author: Springate, Christopher Michael Kevin
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/31160