Sensitivity of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase to external stimuli and its relationship to in vivo rates of cholesterol synthesis in the fetal rat
During gestation the fetus requires cholesterol for membrane accretion, steroidogenesis and lipoprotein synthesis. Very little is known, however, about the mechanisms which regulate cholesterol synthesis in the fetus. When the bile-acid binding resin cholestyramine (CY) is fed to rats throughout ge...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/31011 |