Regulation of budding yeast kinetochore proteins by SUMO modification

Genome stability is a fundamental requirement for the stable propagation of eukaryotic cells, maintenance of phenotype, and cell viability. For example, aneuploidy (abnormal chromosome number), is a hallmark of most human cancers, and can be attributed to increased rates of chromosome instability in...

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Bibliographic Details
Main Author: Montpetit, Benjamen H. W.
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/30958