The role of the ATP-Binding Cassette transporter A1 in Alzheimer Disease neuropathology and brain lipoprotein metabolism
The ATP-Binding Cassette transporter A1 (ABCA1) is a ubiquitously expressed protein that mediates the efflux of cholesterol and phospholipids from the plasma membrane onto lipid poor apolipoproteins (apos), such as apoA-l and apoE. Outside the central nervous system (CNS), this process constitute...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/30889 |