Functional heterogeneity of adult mouse bone marrow hematopoietic stem cells

The mammalian blood-forming system sustains physiologically required levels of mature blood cells by supporting their continuous generation from a rare population of undifferentiated, self-sustaining pluripotent hematopoietic "stem" cells (HSCs). Throughout adult life HSCs are located p...

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Bibliographic Details
Main Author: Dykstra, Bradford John
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/30860