The investigation of a novel BRCA2-associated gene, EMSY, on chromosome 11Q13 in breast and ovarian cancer

EMSY is a novel gene encoding a protein that binds to the tumor suppressor BRCA2. EMSY maps to 11q13, a region commonly amplified in breast cancer, and is located 6 Mb telomeric to CCND1. However, the role of EMSY amplification in breast and ovarian cancer is largely unknown. Here we present evid...

Full description

Bibliographic Details
Main Author: Brown, Lindsay Anne
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/30747