Use of the fluorescent probe 1-N-phenyl napthylamine to study the interactions of aminoglycoside antibiotics with the outer membrane of Pseudomonas aeruginosa
The mode of interaction of the polycationic aminoglycoside antibiotics with the surface of Pseudomonas aeruginosa cells was studied using the hydrophobic fluorescent probe 1-N-phenyl napthylamine (NPN). Addition of the aminoglycoside gentamicin to intact cells in the presence of NPN led to a shi...
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| Language: | English |
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University of British Columbia
2010
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| Online Access: | http://hdl.handle.net/2429/24721 |