Nuclear retention of topical glucocorticoids and absence of cross-linking with DNA in cultured dermal fibroblasts

The principal mechanism by which glucocorticoids exert their physiological effects is by alterations of DNA metabolism. Studies have been done to clarify the nuclear sites of human and mouse L-929 fibroblasts, with which the topical glucocorticoids, hydrocortisone (HC) and triamcinolone acetonide (...

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Bibliographic Details
Main Author: Au, Diana Shu-Lian
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/22601