A formal total synthesis of 9-isocyanopupukeanane
A synthesis of (±)-9-pupukeanone (7) is described. The key reaction was the establishment of the tricyclic carbon skeleton of 7 by means of an intramolecular Diels-Alder cycloaddition. The 1,3-cyclohexanedione 48 was obtained from ethyl methacrylate and ethyl 2-methylacetoacetate by a Michael addit...
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| Language: | English |
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2010
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| Online Access: | http://hdl.handle.net/2429/22563 |