The role of metabolic activation of chemical precarcinogens in the induction of DNA damage and repair in mammalian cells

It has been proposed that DNA alterations may be involved in the "early" stages of chemical carcinogenesis. The relationship between metabolic activation of chemical precarcinogens, DNA damage induced by reactive carcinogenic metabolites, and repair of the damaged DNA was therefore investi...

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Bibliographic Details
Main Author: Laishes, Brian Anthony
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/19625