G₂ DNA damage checkpoint : inhibitors and there potential for anticancer treatment

In response to DNA damage, cell survival can be enhanced by activation of DNA repair mechanisms and of checkpoints that delay cell cycle progression to allow more time for DNA repair. G₂ checkpoint inhibitors can force cells arrested in G₂ phase by DNA damage to enter mitosis thereby enhancing the k...

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Bibliographic Details
Main Author: Sturgeon, Christopher Michael
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/18578