YB-1 is a downstream component of the PI3K/Akt signaling pathway and regulates EGFR in breast carcinoma : a mechanism for breast cancer growth

High level of activated or phosphorylated serine/threonine kinase Akt is commonly observed in aggressive breast cancer. Hence, the Akt signaling pathway has become a popular target for therapeutic interventions. Previously our lab discovered that phosphorylated Akt is co-expressed with a transcripti...

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Bibliographic Details
Main Author: Wu, Chia-Cheng Joyce
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/18400