Chemical studies of anti-inflammatory secondary metabolites from marine sponges

SHIP is a 145 kDa SH2-domain-containing inositol 5-phosphatase. It has been proposed that upregulation of SHIP activity with small molecule agonists of SHIP could control inflammation. At the outset of the research there were no known modulators of SHIP activity. A library of marine invertebrate...

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Bibliographic Details
Main Author: Yang, Lu
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/18389