Aberrant hypermethylation of Xq12 in lymphoma

It has been well established that abnormal CpG island promoter methylation in cancer is associated with the epigenetic silencing of tumour suppressor genes, genes that when inactivated predispose a cell to malignancy. Such aberrant methylation was seen for the androgen receptor (AR) located on the X...

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Bibliographic Details
Main Author: Quint, Désirée
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/18127

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