Aberrant hypermethylation of Xq12 in lymphoma
It has been well established that abnormal CpG island promoter methylation in cancer is associated with the epigenetic silencing of tumour suppressor genes, genes that when inactivated predispose a cell to malignancy. Such aberrant methylation was seen for the androgen receptor (AR) located on the X...
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Language: | English |
Published: |
2010
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Online Access: | http://hdl.handle.net/2429/18127 |