Binding and metabolism of tetrachlorobiphenyls by Cytochrome P450 enzymes : structure-activity relationships

Polychlorinated biphenyls (PCBs) are a class of persistent organic pollutants that bioaccumulate in humans and wildlife. Cytochrome P450 (CYP) enzymes play a critical role in the biotransformation of PCBs. The objective of this study was to explore structure-activity relationships between the chlori...

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Bibliographic Details
Main Author: Edwards, Patrick Robert
Language:English
Published: 2010
Online Access:http://hdl.handle.net/2429/17929