Activation and function of the Rap GTPases in B lymphocytes

Multiple receptors on the surface of B cells are involved in the regulation of B cell development, trafficking and activation. The chemokine SDF-1 and its receptor CXCR4 mediate the retention of B cell progenitors in the bone marrow during development while the trafficking of mature B cells into...

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Bibliographic Details
Main Author: McLeod, Sarah Jean
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/17254