Characterization of mammalian Asx-like genes and role of Asx-like-1 in development and hematopoiesis

Polycomb Group (PcG) chromatin regulatory proteins maintain repression of Hox genes during development, leading to posterior homeotic transformations in the absence of gene product. Conversely, trithorax Group (trxG) proteins maintain activation of Hox genes and trxG null mutants exhibit anterior tr...

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Bibliographic Details
Main Author: Fisher, Cynthia
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/16877