Involvement of 3-phosphoinositide-dependent kinase 1 (PDK1) in the regulation of nitric oxide expression in LPS-stimulated macrophages
Macrophages are part of the innate immune system playing an important role in intestinal inflammation, and amplify the inflammatory response through the activation of Th-1 cytokines including nitric oxide (NO). Macrophages become activated as a result of exposure to microbial product lipopolysaccari...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/16842 |