Mechanistic studies of the enzymes involved in the biosynthesis of CMP-N, N'-diacetyllegionaminic acid and UDP-D-apipose
This thesis focuses on the biosynthesis of two sugar nucleotides. The enzymes responsible for the biosynthesis of N,N’-diacetyllegionaminic acid in Legionella pneumophila are identified for the first time. All three genes (neuA,B, C) demonstrated sequence homology to the genes involved in sialic aci...
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Format: | Others |
Language: | English |
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University of British Columbia
2009
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Online Access: | http://hdl.handle.net/2429/15881 |