Mechanistic studies of the enzymes involved in the biosynthesis of CMP-N, N'-diacetyllegionaminic acid and UDP-D-apipose

This thesis focuses on the biosynthesis of two sugar nucleotides. The enzymes responsible for the biosynthesis of N,N’-diacetyllegionaminic acid in Legionella pneumophila are identified for the first time. All three genes (neuA,B, C) demonstrated sequence homology to the genes involved in sialic aci...

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Bibliographic Details
Main Author: Glaze, Pavel Alexander
Format: Others
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/15881