Hepatic microsomal bile acid biotransformation : identification of metabolites and cytochrome p450 enzymes involved

Bile acids are end-products of cholesterol metabolism and essential for absorption of dietary lipids in the body. Impaired bile flow leads to hepatic bile acid accumulation and liver damage. Hepatic microsomal oxidation offers a potential mechanism for efficient elimination of bile acids. The presen...

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Bibliographic Details
Main Author: Deo, Anand K.
Format: Others
Language:English
Published: University of British Columbia 2009
Online Access:http://hdl.handle.net/2429/15222