Modulation of insulinotropic hormone bioactivity with a focus on clucose-dependent insulinotropic polipeptide (GIP) and its receptor
Insulin secretory responses to oral glucose are compromised in type 2 diabetes. GIP receptor desensitization and internalization were studied as possible mechanisms for the blunted responsiveness to GIP in the human disease, employing in vitro cellular models. Using clonal insulin producing tumour c...
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| Format: | Others |
| Language: | English |
| Published: |
2009
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| Online Access: | http://hdl.handle.net/2429/14867 |