Regulation of muscle contraction by Troponin C

It is generally believed that calcium binding to Troponin C (TnC) in striated muscle acts as a simple switch, enabling tropomyosin to unblock myosin-binding sites on actin filaments. TnC has two domains, each containing a pair of structurally homologous sites. The high-affinity Ca2 +/Mg2 + bindin...

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Bibliographic Details
Main Author: Leblanc, Louise Ellen
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/14768