Alterations in transcription factor binding in anergized human CD4+T- lymphocytes
Background: The mechanisms responsible for the induction of human clonal anergy are not well understood. We have utilized an in vitro model of human T-cell anergy to explore the perturbations in cell signaling at the level of IL-2 gene transcription, and to define the contribution of other cytoki...
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| Format: | Others |
| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/14622 |