Liposomal encapsulation of irinotecan and potential for the use of liposomal drug in the treatment of liver metastases associated with advanced colorectal cancer

Colorectal cancer is the second leading cause of cancer mortality in North America, primarily because of a high incidence of hepatic metastases, which are relatively unresponsive to the systemic chemotherapy. Irinotecan, a camptothecin analogue recently approved for used in conjunction with 5-fluoro...

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Bibliographic Details
Main Author: Messerer, Corrie Lynn
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/13284