To investigate the cellular origin within periportal zone of liver tumor initiation using Mir122a-null mouse model

博士 === 國立陽明大學 === 生命科學系暨基因體科學研究所 === 107 === Hepatocellular carcinoma (HCC) is the major liver malignancy with high morbidity and mortality. MicroRNA-122a (Mir122a) is a tumor suppressor miRNA and is frequently down-regulated in human HCC with a poor prognosis. In mice, Mir122a deficiency causes liv...

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Bibliographic Details
Main Authors: Wei-Ling Tu, 涂瑋玲
Other Authors: Chun-Ming Chen
Format: Others
Language:zh-TW
Published: 2018
Online Access:http://ndltd.ncl.edu.tw/handle/e7b59s