Gut Bacterial β-Glucuronidases: Structural Basis of Substrate Specificity, Inhibitor Potency and Selectivity to Provide a Solution for Xenobiotic-Induced Toxicity

博士 === 國立中興大學 === 生物科技學研究所 === 107 === Gut bacterial β-D-glucuronidases (GUSs) catalyze the removal of glucuronic acid from liver-produced β-D-glucuronides. These reactions can have deleterious consequences when they reverse xenobiotic metabolism. The human gut contains hundreds of GUSs of variable...

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Bibliographic Details
Main Authors: Punsaldulam Dashnyam, 朋莎朗
Other Authors: Chun-Hung Lin
Format: Others
Language:en_US
Published: 2019
Online Access:http://ndltd.ncl.edu.tw/cgi-bin/gs32/gsweb.cgi/login?o=dnclcdr&s=id=%22107NCHU5111019%22.&searchmode=basic