The Role of HIV-1 p6pol Transframe Region in Modulating Protease Activation

博士 === 國立陽明大學 === 臨床醫學研究所 === 106 === Abstract HIV-1 protease (PR) is encoded by pol, which is initially translated as a Pr160gag-pol polyprotein by a ribosomal frameshift event. PR functions as a homodimer mediating virus maturation following virus budding. Gag-Pol dimerization is believed to trigg...

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Bibliographic Details
Main Authors: Fu-Hsien Yu, 于福賢
Other Authors: Chin-Tien Wang
Format: Others
Language:en_US
Published: 2018
Online Access:http://ndltd.ncl.edu.tw/handle/gr95s8