Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome
博士 === 國立臺灣大學 === 生化科學研究所 === 106 === Death domain (DD)-fold assemblies play a crucial role in regulating the signaling to cell survival or death. Here we report the crystal structure of the caspase recruitment domain (CARD)-CARD disk of the human apoptosome. The structure surprisingly reveals that...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2018
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| Online Access: | http://ndltd.ncl.edu.tw/handle/q69t93 |