A selective Aurora A inhibitor, MLN8237, induces cellular Aurora A expression increase and centrosomal abnormality.

碩士 === 國立中興大學 === 生命科學系所 === 106 === Aurora A is a serine/threonine kinase which primarily localizes in the centrosome and mitotic spindle and responds for centrosome maturation, separation, spindle formation and mitotic entry. Therefore, Aurora A plays an important regulator to mitosis and meiosis...

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Bibliographic Details
Main Authors: Chih-Ying Chang, 張智瑩
Other Authors: Ho Lin
Format: Others
Language:zh-TW
Published: 2018
Online Access:http://ndltd.ncl.edu.tw/handle/vx29ra