Epigenetic Regulation of HDAC1 SUMOylation As an Endogenous Defense Against Aβ Toxicity in a Mouse Model of Alzheimer’s Disease
博士 === 國防醫學院 === 生命科學研究所 === 105 === Amyloid-β (Aβ) produces neurotoxicity in the brain and causes neuronal death, but the endogenous defense mechanism that is activated on Aβ insult is less well known. Here we found that acute Aβ increases the expression of PIAS1 and Mcl-1 via activation of MAP...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2017
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| Online Access: | http://ndltd.ncl.edu.tw/handle/vqf8p8 |