Studying the key residues affecting the ligand binding affinity of Dihydrofolate reductase.

碩士 === 國立交通大學 === 生物資訊及系統生物研究所 === 105 === The function of dihydrofolate reductase (DHFR) is to catalyze the reduction of dihydrofolate (DHF) to tetrahydrofolic acid (THF) with NADPH as a coenzyme. The catalytic product THF is essential for amino acid catabolism and DHFR is the only enzyme in cells...

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Bibliographic Details
Main Authors: Huang, Chen-Hua, 黃振華
Other Authors: Kao, Ya-Ting
Format: Others
Language:zh-TW
Published: 2016
Online Access:http://ndltd.ncl.edu.tw/handle/20962638867562929076