Design and Synthesis a Water-soluble Group for Ether-linkage of 10-Hydroxycamptothecin Prodrug
碩士 === 嘉南藥理大學 === 藥學系 === 105 === Camptothecin has good anti-cancer activity, and current clinical use of two derivatives are Topotecan and Irinotecan which improve poor water solubility of Camptothecin by chemical modification. However, the lack of drugs specificity of tumor will cause severe side...
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2017
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| Online Access: | http://ndltd.ncl.edu.tw/handle/686w4t |