The PPARγ-SETD8 axis constitutes an epigenetic, p53-independent checkpoint on p21-mediated cellular senescence

博士 === 長庚大學 === 生物醫學研究所 === 105 === Cellular senescence is a permanent proliferative arrest triggered by genome instability or aberrant growth stresses, acting as a protective or even tumor-suppressive mechanism. While several key aspects of gene regulation have been known to program this cessation...

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Bibliographic Details
Main Authors: Chieh Tien Shih, 施杰廷
Other Authors: C. M. Tan
Format: Others
Language:en_US
Published: 2017
Online Access:http://ndltd.ncl.edu.tw/handle/f23xgv