Investigation of liposomal formulation of SN-38 fortargeting drug delivery system

碩士 === 高雄醫學大學 === 藥學系碩士班 === 104 === SN-38(7-ethyl-10-hydroxycamptothecin), the active metabolite of the commercial drug, irinotecan, is approximately 100-1000-fold cytotoxicity than irinotecan. Due to the poor solubility, instability in alkaline and severe side effect, SN-38 has not been used in th...

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Bibliographic Details
Main Authors: Yi-Jhun Wu, 吳怡諄
Other Authors: Yi-Ping Fang
Format: Others
Language:zh-TW
Published: 2016
Online Access:http://ndltd.ncl.edu.tw/handle/04424047816866791766