Immunological basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction

博士 === 國立臺灣大學 === 微生物學研究所 === 103 === Allopurinol is a commonly prescribed drug for symptomatic hyperuricemia and its complication, gout. The major limitation of allopurinol is that it is a frequent cause of severe cutaneous adverse reactions (SCARs), including hypersensitivity syndrome (HSS), Steve...

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Bibliographic Details
Main Authors: Chia-Hsien Lin, 林嘉嫻
Other Authors: 陳垣崇
Format: Others
Language:en_US
Published: 2014
Online Access:http://ndltd.ncl.edu.tw/handle/zsjc5u