Identify protein Shugoshin-1 as a potential therapeutic target for hepatocellular carcinoma

博士 === 國立清華大學 === 分子與細胞生物研究所 === 103 === Protein Shugoshin-1 (Sgo1) functions to protect centromeric cohesion and is essential for proper chromosome segregation and genomic integrity. During mitosis, Plk-1 phosphorylates SA2 subunit of cohesin, and thereby cohesin dissociates from chromosome arm. In...

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Bibliographic Details
Main Authors: Wang, Lyu Han, 王律涵
Other Authors: Wang, Lily Hui-Ching
Format: Others
Language:en_US
Published: 2015
Online Access:http://ndltd.ncl.edu.tw/handle/545czw