Identify protein Shugoshin-1 as a potential therapeutic target for hepatocellular carcinoma
博士 === 國立清華大學 === 分子與細胞生物研究所 === 103 === Protein Shugoshin-1 (Sgo1) functions to protect centromeric cohesion and is essential for proper chromosome segregation and genomic integrity. During mitosis, Plk-1 phosphorylates SA2 subunit of cohesin, and thereby cohesin dissociates from chromosome arm. In...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2015
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Online Access: | http://ndltd.ncl.edu.tw/handle/545czw |